Bubba's Buddies Funds New Research For Treatment of Degenerative Myelopathy (DM) in Partnership with the AKC Canine Health Foundation.

Bubba's Buddies Funds New Research For Treatment of Degenerative Myelopathy (DM) in Partnership with the American Kennel Club Canine Health Foundation.

DONATE HERE To Help Us Fund Future Research

Bubba's Buddies has focused its efforts raising funds to help jumpstart a new clinical trial by the 4 Universities that make up Project DM.  Collectively we were able to raise and donate over $60,000 to the AKC Canine Health Foundation to help fund the grant for this first of its kind treatment study for Degenerative Myelopathy.

On March 1, 2023 we are proud to announce that our efforts and your donations has paid off. In partnership with the AKC Canine Health Foundation, we were able to bring this Degenerative Myelopathy (DM) treatment study into reality. Read on to learn about this exciting new study with Riluzole as a Neuroprotectant (treatment) in Canine Degenerative Myelopathy.

According to the AKC Canine Health Foundation

"This FDA approved drug has been shown to extend survival in ALS patients.  The long-term goal is to establish effective clinical strategies for treatment of canine DM through the efficient conduct of veterinary clinical trials.  Toward this goal, the research team has recently worked to establish a collaborative network of canine DM researchers (Project DM), designed and implemented a longitudinal DM patient registry to enhance data collection and observational studies, and built a platform trial design, which can serve to evaluate novel therapies and disease measures in a standardized way across multiple institutions.  Investigators hypothesize that riluzole, at an optimized dose, will delay disease progression, as evidenced by alteration of both disease-associated biomarkers and clinical outcome measures, therefore improving overall longevity and quality of life in dogs with DM.  This hypothesis will be tested through the following aims:  1) evaluate oral riluzole safety and establish a candidate dose; 2) conduct a clinical trial for therapeutic efficacy; and 3) demonstrate that neurofilament light, a structural protein found in neurons, is a valuable biological marker to assess the clinical progression of DM in dogs."

Click Here to learn more about this grant and study.

If you or anyone you know has a dog with DM symptoms, please consider participating in this study we urge you to visit the link above for information and ways to become involved.

We are far from finding a cure for this terrible disease, and Bubba's Buddies mission is to find a cure. We would love you to consider donating to help us push on and fund the next trials.